NFL Predictions: Week 1 Games, Best Prices and Super Bowl Futures
Here are the NFL predictions and best available prices for the Week 1 slate opening September 10, 2026, plus current Super Bowl futures. Every odds figure below comes from our sampled pricing data and names the sportsbook posting the best number, so you can see where a line actually sits before you back it. We do not publish tracked win-rate claims — the value here is price comparison and matchup context across nine licensed US sportsbooks. Remember: US sports betting is state-by-state, the minimum age is 21, and availability depends on your state regulator.
Week 1 NFL games and where the best price sits
The opener between the Seattle Seahawks and New England Patriots (Sept 10) has the Seahawks at 1.54 on DraftKings, with the Patriots priced at 2.70 on Fanatics. That gap tells you the market treats Seattle as a clear favorite at home.
The Sunday slate (Sept 13) has the sharpest disagreements worth shopping:
- Houston Texans vs Buffalo Bills — near coin flip: Texans 1.98 (DraftKings) vs Bills 1.95 (BetMGM). This is the game where line shopping matters least on the moneyline but most on the spread and player props.
- Indianapolis Colts vs Baltimore Ravens — Ravens 1.57 (DraftKings) on the road; Colts 2.65 (BetRivers) if you want the underdog.
- Jacksonville Jaguars vs Cleveland Browns — the widest gap on the board: Jaguars 1.29 (Fanatics) against Browns 4.20 (FanDuel).
- Detroit Lions vs New Orleans Saints — Lions 1.31 (DraftKings), Saints 3.70 (BetRivers).
- Cincinnati Bengals vs Tampa Bay Buccaneers — Bengals 1.53 (BetMGM), Bucs 2.76 (FanDuel).
Saturday night's Rams–49ers (Sept 11) is the marquee divisional matchup: Rams 1.56 (Fanatics) at home, 49ers 2.72 (FanDuel). Pittsburgh Steelers host the Atlanta Falcons at 1.62 (FanDuel), Carolina Panthers vs Chicago Bears has Chicago at 1.68 (DraftKings), and Tennessee Titans vs New York Jets sits at Titans 1.75 (FanDuel), Jets 2.25 (Fanatics).
Across this slate DraftKings and FanDuel post the best price most often, which lines up with our sampled odds data: DraftKings holds the best-price share on roughly 54% of markets sampled, with FanDuel and Fanatics next.
Super Bowl futures: current best prices
If you are betting the season rather than one Sunday, here is where the outright Super Bowl odds sit, with the best of four sampled books named:
- Los Angeles Rams — 6.5 (DraftKings), the shortest price on the board
- Buffalo Bills — 12 (FanDuel)
- Seattle Seahawks — 12 (BetMGM)
- Baltimore Ravens — 13 (FanDuel)
- Kansas City Chiefs — 18 (FanDuel)
- Los Angeles Chargers — 18 (BetMGM)
- Philadelphia Eagles — 19 (BetMGM)
- Detroit Lions — 20 (DraftKings)
- San Francisco 49ers — 20 (DraftKings)
- Denver Broncos — 21 (BetRivers)
Futures prices drift all season on injuries and results, so the book with the best number today may not hold it in Week 8. Check current futures odds before committing, and note that a longer price at one book can outweigh a small margin difference elsewhere.
Which sportsbook fits your NFL betting
Price and features differ meaningfully between these operators. Match the book to how you bet:
- Best overall market depth: bet365 rates highest on market coverage (9.6) and sports depth (9.5) and includes Bet Builder, Cash Out and Live Streaming. Choose it if you want broad NFL markets and in-play tools.
- Best price share on the sample: DraftKings takes the best price on about 54% of sampled markets and carries Same Game Parlay and Fast Payout. A strong default for line shoppers.
- Tightest margin among the majors: Fanatics posted the lowest average margin (~4.2%) in our sample, edging DraftKings, with FanDuel close behind (~4.5%). Lower margin generally means better value across a book's board.
- Avoid for value if margin matters most: BetRivers (~6.3%) and Caesars (~5.3%) carried wider sampled margins, though BetRivers scores well on withdrawals (8.6).
All nine are licensed by state regulators, use a $10 minimum deposit and quote withdrawals of 0–24h. The practical way to bet NFL is to keep two or three accounts open and take whichever posts the best number on your selection — the tables above show those differences are real.
How we compare NFL odds
Our best-price figures come from sampled market data per operator — DraftKings (1,068 markets sampled), Caesars (906), FanDuel (596), Fanatics (466), BetMGM (438) and BetRivers (480). From that we report each book's best-price share and average margin, then name the operator holding the top number on each game.
We do not publish predicted scorelines dressed up as guaranteed outcomes, and we do not track a win-rate archive, so we make no accuracy claims. Treat every price as a snapshot: NFL lines move on injury reports, weather and money, especially in the days before Sunday kickoff. Compare live odds and market movers before you place a bet.
